135643-48-0

Upstream product

• 85-44-9 phthalic anhydride 
• 109-77-3 malononitrile 

Downstream Products

• 1541898-63-8 5-amino-1-benzyl-8-nitro-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-66-2 5-amino-8-(p-flurobenzoyl)-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-86-6 6'-amino-9'-(p-bromobenzoyl)-3-oxo-1',2',3',4'-tetrahydro-3H-spiro[isobenzofuran-1,8'-pyrido[1,2-a]pyrimidine]-7'-carbonitrile 
• 1245790-82-2 6'-amino-9'-(p-methoxybenzoyl)-3-oxo-1',2',3',4'-tetrahydro-3H-spiro[isobenzofuran-1,8'-pyrido[1, 2-a]pyrimidine]-7'-carbonitrile 
• 1245790-84-4 6'-amino-9'-(p-chlorobenzoyl)-3-oxo-1',2',3',4'-tetrahydro-3H-spiro[isobenzofuran-1,8'-pyrido[1,2-a]pyrimidine]-7'-carbonitrile 
• 1245790-62-8 5-amino-8-(p-methoxybenzoyl)-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-64-0 5-amino-8-(p-chlorobenzoyl)-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-80-0 6'-amino-9'-(p-methylbenzoyl)-3-oxo-1',2',3',4'-tetrahydro-3H-spiro[isobenzofuran-1,8'-pyrido[1,2-a]pyrimidine]-7'-carbonitrile 
• 1245790-68-4 8-(1,1'-biphenyl)-5-amino-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-78-6 6'-amino-9'-benzoyl-3-oxo-1',2',3',4'-tetrahydro-3H-spiro[isobenzofuran-1,8'-pyrido[1,2-a]pyrimidine]-7'-carbonitrile 
• 1245790-60-6 5-amino-8-(p-methylbenzoyl)-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 1245790-58-2 5-amino-8-benzoyl-3'-oxo-2,3-dihydro-1H,3'H-spiro[imidazo[1,2-a]pyridine-7,1'-isobenzofuran]-6-carbonitrile 
• 19357-24-5 2-(4-phenoxyphenyl)-1H-isoindole-1,3(2H)-dione 
• 4870-16-0 N-anilinophthalimide 

Relevant academic research and scientific papers

Design, synthesis and insecticidal activity of spiro heterocycle containing neonicotinoid analogs

Spiro heterocycles frequently occur in bioactive molecules. In the pursuit of neonicotinoids with spiro heterocycles, three types of novel neonicotinoids with spirobenzofuranone, spirooxindole or spiroacenaphythylenone framework were designed and synthesized. Insecticidal evaluation showed that some of spirobenzofuranone containing neonicotinoids exhibited moderate activity against cowpea aphid, armyworm or brown planthopper.