1356536-08-7

Basic information

• Product Name: N-[2-n-butyl-3-[4-[3 (-di-n-butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]-N'-ethoxycarbonyl-methanesulfonamide
• Synonyms: N-[2-n-butyl-3-[4-[3 (-di-n-butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]-N'-ethoxycarbonyl-methanesulfonamide
• CAS NO: 1356536-08-7
• Molecular Weight: 628.83
• Mol File: 1356536-08-7.mol

Chemical Properties

• CAS DataBase Reference: N-[2-n-butyl-3-[4-[3 (-di-n-butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]-N'-ethoxycarbonyl-methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-n-butyl-3-[4-[3 (-di-n-butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]-N'-ethoxycarbonyl-methanesulfonamide(1356536-08-7)
• EPA Substance Registry System: N-[2-n-butyl-3-[4-[3 (-di-n-butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]-N'-ethoxycarbonyl-methanesulfonamide(1356536-08-7)

Safety Data

• Hazardous Substances Data: 1356536-08-7(Hazardous Substances Data)

Upstream product

• 141645-51-4 5-amino 2-n-butyl benzofuran 
• 437652-07-8 N-(2-butyl-2,3-dihydro-5-benzofuranyl)methanesulfonamide 

Downstream Products

• 141626-36-0 dronedarone 

Relevant articles and documents

Novel Process for the Preparation of Dronedarone

The subject of the invention is a novel process for the preparation of N-[2-n-butyl-3-{4-[(3-di-n-butylamino)-propoxy]benzoyl}benzofuran-5-yl]-methanesulfonamide of formula I: and pharmaceutically acceptable salts thereof wherein the acyl group of the benzofuran derivative of the general formula II: where R represents C1-4 alkyl-, C1-4 alkoxy- or aryl group, is selectively cleaved and if desired, the resulting compound of formula I is transformed into its salt.