1356668-27-3Relevant academic research and scientific papers
Fe-promoted radical cyanomethylation/arylation of arylacrylamides to access oxindoles via cleavage of the sp3 C-H of acetonitrile and the sp2 C-H of the phenyl group
Pan, Changduo,Zhang, Honglin,Zhu, Chengjian
supporting information, p. 361 - 364 (2015/02/05)
Radical cyanomethylation/arylation of arylacrylamides to access oxindoles with acetonitrile as the radical precursor is described. This reaction involves dual C-H bond functionalization, including the sp3 C-H of acetonitrile and the sp2/s
Palladium-catalyzed oxidative arylalkylation of activated alkenes: Dual C-H bond cleavage of an arene and acetonitrile
Wu, Tao,Mu, Xin,Liu, Guosheng
supporting information; experimental part, p. 12578 - 12581 (2012/02/04)
Not one but two: The title reaction proceeds through the dual C-H bond cleavage of both aniline and acetonitrile (see scheme). The reaction affords a variety of cyano-bearing indolinones in excellent yield. Mechanistic studies demonstrate that this reaction involves a fast arylation of the olefin and a rate-determining C-H activation of the acetonitrile. Copyright
