1356691-92-3Relevant academic research and scientific papers
Stereoselective synthesis of N-aryl proline amides by biotransformation- Ugi-Smiles sequence
Znabet, Anass,Blanken, Sara,Janssen, Elwin,De Kanter, Frans J. J.,Helliwell, Madeleine,Turner, Nicholas J.,Ruijter, Eelco,Orru, Romano V. A.
, p. 941 - 944 (2012)
An efficient combination of MAO-N-catalyzed desymmetrization of cyclic meso-amines with Ugi-Smiles multicomponent chemistry produced optically pure N-aryl proline amides. This method represents the first report of a fully asymmetric Ugi-Smiles process.
