5470-65-5

Basic information

• Product Name: 3-Bromo-4-nitrophenol
• Synonyms: 3-Bromo-4-nitrophenol;3-Bromo-4-nitro-phenol;NSC 2796;NSC 27960;Phenol, 3-broMo-4-nitro-
• CAS NO: 5470-65-5
• Molecular Formula: C₆H₄BrNO₃
• Molecular Weight: 218.01
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 5470-65-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 125-1270C
• Boiling Point: 306.7 °C at 760 mmHg
• Flash Point: 139.3 °C
• Appearance: brown solid
• Density: 1.881 g/cm³
• Vapor Pressure: 0.00042mmHg at 25°C
• Refractive Index: 1.651
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 6.32±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-4-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-4-nitrophenol(5470-65-5)
• EPA Substance Registry System: 3-Bromo-4-nitrophenol(5470-65-5)

Safety Data

• Hazardous Substances Data: 5470-65-5(Hazardous Substances Data)

Usage

Chemical Properties

Brown Solid

InChI:InChI=1/C6H4BrNO3/c7-5-3-4(9)1-2-6(5)8(10)11/h1-3,9H

Upstream product

• 591-20-8 3-Bromophenol 
• 7664-93-9 sulfuric acid 
• 700-36-7 2-bromo-4-fluoronitrobenzene 
• 371-40-4 4-fluoroaniline 
• 51686-78-3 2,4-dibromonitrobenzene 
• 634603-83-1 3-bromo-4-nitrosophenol 
• 13362-38-4 2-bromo-p-quinone monooxime 
• 577-19-5 2-nitrophenyl bromide 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 394-41-2 3-fluoro-4-nitrophenol 
• 165190-62-5 4-(benzyloxy)-2-bromo-1-nitrobenzene 
• 19046-86-7 3-bromo-2,4,6-trinitro-phenol 
• 116632-29-2 5-bromo-2,4-dinitro-phenol 
• 57279-69-3 2-bromo-4-ethoxy-1-nitro-benzene 
• 98447-30-4 2-bromo-4-methoxy-1-nitrobenzene 
• 123028-00-2 3-bromo-4-nitrophenyl trifluoromethanesulfonate 
• 74440-80-5 4-amino-3-bromo-phenol 

Relevant articles and documents

Preparation method of 3-bromo-4-bromonitrophenol

The invention discloses an industrial preparation method of 3-bromo-4-bromonitrophenol. According to the industrial preparation method of the 3-bromo-4-bromonitrophenol, p-fluoroaniline serves as an initial raw material, and the 3-bromo-4-bromonitrophenol

AMPHIPATHIC AND OTHER DOUBLE-SIDED ALPHA-HELIX MIMETICS BASED ON A 1,2-DIPHENYLACETYLENE SCAFFOLD

Small-molecule scaffolds based on 1,2-diphenylacetylene that accurately replicate the spatial and angular projections of several side chains on both faces of an α-helix, specifically the i and i+7 side chains on one face, and the i and i+2 side chains on the other. The amphipathic α-helix mimetic can be used to disrupt disease-promoting protein-protein interactions that are mediated by α-helices.

Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffold

In order to mimic amphipathic α-helices, a novel scaffold based on a 1,2-diphenylacetylene was designed. NMR and computational modeling confirmed that an intramolecular hydrogen bond favors conformations of the 1,2-diphenylacetylene that allow for accurat