1356822-77-9

Upstream product

• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 303006-89-5 1,4-dimethyl-2,5-di(4’,4’,5’,5’-tetramethyl[1,3,2’]dioxaborolan-2’-yl)benzene 
• 73183-34-3 bis(pinacol)diborane 
• 1074-24-4 2,5-dibromo-p-xylene 

Downstream Products

• 1535164-77-2 1-(4-(bromomethyl)-2,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-N,N,N-trimethylmethanaminium bromide 

Relevant academic research and scientific papers

ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block

Down at the crossed code: Novel arylboronic ester and biarylboronic ester derivatives were synthesized. Compound 1 can be activated by hydrogen peroxide to release 2,5-bis(trimethylammonium) benzyl-1,4-diol (2), which leads to interstrand cross-link formation and DNA alkylation (see scheme). Compound 1 provides a novel building block for the development of H2O 2-targeting anticancer prodrugs. Copyright

Conjugated microporous polymers with azide groups: A new strategy for postsynthetic fluoride functionalization and effectively enhanced CO2 adsorption properties

A series of conjugated microporous polymers (CMPs) have been synthesized based on zinc-porphyrin building blocks. Azide groups incorporated within the pores of the CMPs were subjected to alkyne click conditions via a facile, one-step quantitative procedure, the resultant porous frameworks exhibited enhanced CO2 sorption properties.

ANTI-CANCER AGENTS

Described herein are compounds that may be selectively activated to produce active anti-cancer agents in tumor cells. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of treating cancer using the compounds.