1356853-98-9

Upstream product

• 1356853-97-8 N-(3,4-dimethylphenyl)-N-(4-nitrobenzyl)methanesulfonamide 
• 355816-01-2 3,4-dimethyl-N-(4-nitrobenzyl)aniline 
• 95-64-7 4-amino-o-xylene 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 1356851-44-9 N-(4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}phenyl)-2-ethoxybenzamide 

Relevant academic research and scientific papers

5-LIPOXYGENASE INHIBITORS

The present invention relates to sulfonamides derivatives as 5-lipoxygenase (5-LO) inhibitors and a process for their synthesis. The present invention also relates to pharmacological compositions containing these sulfonamides derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.