Cas 355816-01-2,3,4-dimethyl-N-(4-nitrobenzyl)aniline

355816-01-2

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Basic information

Product Name: 3,4-dimethyl-N-(4-nitrobenzyl)aniline
Synonyms: 3,4-dimethyl-N-(4-nitrobenzyl)aniline
CAS NO:355816-01-2
Molecular Formula: C₁₅H₁₆N₂O₂
Molecular Weight: 256.29974
EINECS: N/A
Product Categories: N/A
Mol File: 355816-01-2.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(CAS DataBase Reference)
NIST Chemistry Reference: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(355816-01-2)
EPA Substance Registry System: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(355816-01-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 355816-01-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 355816-01-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,5,8,1 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 355816-01:
(8*3)+(7*5)+(6*5)+(5*8)+(4*1)+(3*6)+(2*0)+(1*1)=152
152 % 10 = 2
So 355816-01-2 is a valid CAS Registry Number.

355816-01-2Upstream product

355816-01-2Downstream Products

355816-01-2Relevant academic research and scientific papers

Bisulfite Addition Compounds as Substrates for Reductive Aminations in Water

Bailey, J. Daniel,Iyer, Karthik S.,Leahy, David K.,Li, Xiaohan,Lipshutz, Bruce H.,Thakore, Ruchita R.

, p. 7205 - 7208 (2021/09/22)

Highly valued products resulting from reductive aminations utilizing shelf-stable bisulfite addition compounds of aldehydes can be made under aqueous micellar catalysis conditions. Readily available α-picolineborane serves as the stoichiometric hydride source. Recycling of the aqueous reaction medium is easily accomplished, and several applications to targets in the pharmaceutical industry are documented.

Chemoselective Reductive Aminations in Aqueous Nanoreactors Using Parts per Million Level Pd/C Catalysis

Casotti, Gianluca,Gao, Eugene S.,Jin, Henry S.,Lipshutz, Bruce H.,Takale, Balaram S.,Thakore, Ruchita R.

supporting information, (2020/09/09)

Condensation in recyclable water between aldehydes or ketones and amines occurs smoothly within the hydrophobic cores of nanomicelles, resulting in imine formation that is subject to subsequent reduction leading, overall, to reductive amination. This micellar technology enables the synthesis of several types of pharmaceuticals, a new procedure that relies on only 2000 ppm (0.20 mol %) palladium from commercially available Pd/C. A broad range of substrates can be used under mild conditions, leading to high chemical yields of the desired secondary and tertiary amines.

5-LIPOXYGENASE INHIBITORS

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Page/Page column 69-70, (2012/02/13)

The present invention relates to sulfonamides derivatives as 5-lipoxygenase (5-LO) inhibitors and a process for their synthesis. The present invention also relates to pharmacological compositions containing these sulfonamides derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.

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