355816-01-2

Basic information

• Product Name: 3,4-dimethyl-N-(4-nitrobenzyl)aniline
• Synonyms: 3,4-dimethyl-N-(4-nitrobenzyl)aniline
• CAS NO: 355816-01-2
• Molecular Formula: C₁₅H₁₆N₂O₂
• Molecular Weight: 256.29974
• Mol File: 355816-01-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(355816-01-2)
• EPA Substance Registry System: 3,4-dimethyl-N-(4-nitrobenzyl)aniline(355816-01-2)

Safety Data

• Hazardous Substances Data: 355816-01-2(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 95-64-7 4-amino-o-xylene 
• 41468-11-5 sodium hydroxy(4-nitrophenyl)methanesulfonate 

Downstream Products

• 1356853-97-8 N-(3,4-dimethylphenyl)-N-(4-nitrobenzyl)methanesulfonamide 
• 1356853-98-9 N-(4-aminobenzyl)-N-(3,4-dimethylphenyl)methanesulfonamide 
• 1356851-44-9 N-(4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}phenyl)-2-ethoxybenzamide 

Relevant articles and documents

Bisulfite Addition Compounds as Substrates for Reductive Aminations in Water

Highly valued products resulting from reductive aminations utilizing shelf-stable bisulfite addition compounds of aldehydes can be made under aqueous micellar catalysis conditions. Readily available α-picolineborane serves as the stoichiometric hydride source. Recycling of the aqueous reaction medium is easily accomplished, and several applications to targets in the pharmaceutical industry are documented.

5-LIPOXYGENASE INHIBITORS

The present invention relates to sulfonamides derivatives as 5-lipoxygenase (5-LO) inhibitors and a process for their synthesis. The present invention also relates to pharmacological compositions containing these sulfonamides derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.