1356935-23-3

Basic information

• Product Name: cis-PtCl₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe)
• CAS NO: 1356935-23-3
• Molecular Weight: 875.584
• Mol File: 1356935-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-PtCl₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe)(CAS DataBase Reference)
• NIST Chemistry Reference: cis-PtCl₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe)(1356935-23-3)
• EPA Substance Registry System: cis-PtCl₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe)(1356935-23-3)

Safety Data

• Hazardous Substances Data: 1356935-23-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1356935-09-5 PtCl₂[Ph₂PN(C₆H₄(3-CO₂Me))PPh₂] 

Downstream Products

• 1356935-26-6 cis-PtBr₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe) 
• 1356935-28-8 cis-PtI₂[Ph₂PNH(C₆H₃(3,5-CO₂Me)2)](Ph₂POMe) 

Relevant articles and documents

Square-planar metal(II) complexes containing ester functionalised bis(phosphino)amines: Mild P-N methanolysis and Carene-H cyclometallation

The synthesis of three new ester functionalised bis(phosphino)amines Ph2PN{R}PPh2 [R = C6H4(3-CO 2Me) 1a; C6H3(3,5-CO2Me)2 1b; C6H4(4-CO2Me) 1c] upon stoichiometric reaction of Ph2PCl and the appropriate H2N{R} in Et 2O is described. Reaction of 1 equiv. of 1a-c with MCl 2(cod) (M = Pt, Pd) in CH2Cl2 afforded the dichlorometal(II) complexes PtCl2(1a) 2a, PtCl2(1b) 2b, PtCl2(1c) 2c and PdCl2(1b) 2'b respectively. The corresponding dibromo (and diiodo) platinum(II) complexes 3b (and 4b) were synthesised, in >80% isolated yields, from PtBr2(cod) or PtI 2(cod). When a suspension of 2b in MeOH was stirred at r.t. for ca. 16 h the mixed complex cis-PtCl2[Ph2PNH{R}](Ph 2POMe) 5a [R = C6H3(3,5-CO2Me) 2] was cleanly generated. Metathesis of 5a using excess NaBr or NaI in MeOH/acetone afforded cis-PtBr2[Ph2PNH{R}](Ph 2POMe) 5b or cis-PtI2[Ph2PNH{R}](Ph 2POMe) 5c. Methanolysis of PtCl2(1a) 2a at ambient temperature afforded, in low yield (18%), the regiospecific P,C-orthometallated complex cis-PtCl[Ph2PNH{C6H3(3-CO 2Me)}](Ph2POMe) 6. We speculate the C-H activated complex 6 is obtained via initial formation of cis-PtCl2[Ph 2PNH{C6H4(3-CO2Me)}](Ph 2POMe) 7. A similar observation was also found using 2c whereupon examination of the isolated solid, by 31P{1H} NMR spectroscopy, revealed formation of three complexes namely orthometallated cis-PtCl[Ph2PNH{C6H3(4-CO2Me)}] (Ph2POMe) 9, cis-PtCl[Ph2PNH{C6H 4(4-CO2Me)}](Ph2POMe) 10 and cis-PtCl 2(Ph2POMe)2 8. All new compounds reported here have been characterised by multinuclear NMR and IR spectroscopy, microanalysis and in six cases by single crystal X-ray crystallography. The X-ray structure of cis-PtCl[Ph2PNH{C6H3(3-CO2Me)}] (Ph2POMe) 6 revealed selective C-H cycloplatination at the 6-position (as opposed to the 2-position) of the N-arene ring.