1357010-06-0

Upstream product

• 75553-23-0 (E)-5-phenyl-2-penten-1-ol 
• 639005-99-5 (E)-(5-chloropent-3-en-1-yl)benzene 
• 122-52-1 triethyl phosphite 
• 5324-30-1 diethyl 2-bromoethylphosphonate 
• 104-53-0 3-phenyl-propionaldehyde 
• 1357009-95-0 diethyl {2-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]ethyl}phosphonate 

Downstream Products

• 1357010-11-7 [(3E,5E)-6-cyclohexylhexa-3,5-dien-1-yl]benzene 
• 1357010-12-8 [(3E,5E)-7,7-dimethylocta-3,5-dien-1-yl]benzene 

Relevant academic research and scientific papers

Rhodium(ii)-catalyzed intramolecular formal [4 + 3] cycloadditions of dienyltriazoles: Rapid access to fused 2,5-dihydroazepines

Rhodium(ii)-catalyzed intramolecular [4 + 3] cycloadditions of dienyltriazoles have been developed, which enable the efficient synthesis of various fused 2,5-dihydroazepines. Mechanistically, the titled reaction proceeds via an interesting tandem cyclopropanation/aza-cope rearrangement.

Synthesis of conjugated polyenes via sequential condensation of sulfonylphosphonates and aldehydes

Selective metalation of sulfonylphosphonates results in sufficiently stable carbanions that undergo chemoselective Julia-Kocienski condensation with various aldehydes to provide (E)-allylic phosphonates in good yields and selectivities. The subsequent Horner-Wadsworth-Emmons condensation with aldehydes is used to synthesize various unsymmetrical trans-dienes, trienes, and tetraenes. This methodology is utilized for the concise synthesis of a naturally occurring fluorescent probe for membrane properties, β-parinaric acid.