1357009-95-0Relevant academic research and scientific papers
Rhodium(ii)-catalyzed intramolecular formal [4 + 3] cycloadditions of dienyltriazoles: Rapid access to fused 2,5-dihydroazepines
Tian, Yu,Wang, Yuanhao,Shang, Hai,Xu, Xudong,Tang, Yefeng
supporting information, p. 612 - 619 (2015/02/05)
Rhodium(ii)-catalyzed intramolecular [4 + 3] cycloadditions of dienyltriazoles have been developed, which enable the efficient synthesis of various fused 2,5-dihydroazepines. Mechanistically, the titled reaction proceeds via an interesting tandem cyclopropanation/aza-cope rearrangement.
Synthesis of conjugated polyenes via sequential condensation of sulfonylphosphonates and aldehydes
Cichowicz, Nathan R.,Nagorny, Pavel
supporting information; experimental part, p. 1058 - 1061 (2012/04/05)
Selective metalation of sulfonylphosphonates results in sufficiently stable carbanions that undergo chemoselective Julia-Kocienski condensation with various aldehydes to provide (E)-allylic phosphonates in good yields and selectivities. The subsequent Horner-Wadsworth-Emmons condensation with aldehydes is used to synthesize various unsymmetrical trans-dienes, trienes, and tetraenes. This methodology is utilized for the concise synthesis of a naturally occurring fluorescent probe for membrane properties, β-parinaric acid.
