1357075-63-8

Basic information

• Product Name: (1S)-1-indanyl (R)-2-methoxy-2-phenylpent-3-ynoate
• Synonyms: (1S)-1-indanyl (R)-2-methoxy-2-phenylpent-3-ynoate
• CAS NO: 1357075-63-8
• Molecular Weight: 320.388
• Mol File: 1357075-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S)-1-indanyl (R)-2-methoxy-2-phenylpent-3-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-indanyl (R)-2-methoxy-2-phenylpent-3-ynoate(1357075-63-8)
• EPA Substance Registry System: (1S)-1-indanyl (R)-2-methoxy-2-phenylpent-3-ynoate(1357075-63-8)

Safety Data

• Hazardous Substances Data: 1357075-63-8(Hazardous Substances Data)

Upstream product

• 682352-11-0 (1S,2R,3S,5R,2'R)-6,6-dimethyl-3-(2'-ethoxy-1'-phenyl-1'-oxo-2'-ethylsulfanyl)-2-(O-t-butyl-dimethylsilyl-hydroxymethyl)-bicyclo[3.1.1]heptane 
• 682352-10-9 (1S,2R,3S,5R,2'S)-6,6-dimethyl-3-(2'-ethoxy-1'-phenyl-1'-oxo-2'-ethylsulfanyl)-2-(O-t-butyl-dimethylsilyl-hydroxymethyl)-bicyclo[3.1.1]heptane 
• 1357075-62-7 (S)-(-)-2-methoxy-2-phenylpent-3-ynoic acid 
• 25501-32-0 (S)-indanol 
• 1357075-61-6 (R)-(+)-2-methoxy-2-phenylpent-3-ynoic acid 
• 1357075-60-5 (1S,2R,3S,5R)-2-(O-tert-butyldimethylsilyloxymethylen)-6,6-dimethyl-3-[(1S,2S)-2-methoxy-1-ethoxy-2-phenyl-3-pentyn-1-sulfanyl]bicyclo[3.1.1]heptane 
• 1357075-59-2 (1S,2R,3S,5R)-2-(O-tert-butyldimethylsilyloxymethylen)-6,6-dimethyl-3-[(1R,2R)-2-methoxy-1-ethoxy-2-phenyl-3-pentyn-1-sulfanyl]bicyclo[3.1.1]heptane 
• 1357075-58-1 (1S,2R,3S,5R)-2-(O-tert-butyldimethylsilyloxymethylen)-6,6-dimethyl-3-[(1S,2S)-1-ethoxy-2-phenyl-2-hydroxy-3-pentyn-1-sulfanyl]bicyclo[3.1.1]heptane 
• 1357075-57-0 (1S,2R,3S,5R)-2-(O-tert-butyldimethylsilyloxymethylen)-6,6-dimethyl-3-[(1R,2R)-1-ethoxy-2-phenyl-2-hydroxy-3-pentyn-1-sulfanyl]bicyclo[3.1.1]heptane 

Relevant articles and documents

Diastereoselective preparation of (R)- and (S)-2-methoxy-2-phenylpent-3- ynoic acids and their use as reliable chiral derivatizing agents

Benzoyl-S,O-acetals 1a and 1b were used as chiral auxiliaries to achieve the diastereoselective preparation of both enantiomers of 2-methoxy-2- phenylpent-3-ynoic acids (MPPAs). The latter were condensed with several chiral secondary alcohols and some primary amines to evaluate their potential as chiral derivatizing agents (CDAs). The 1H NMR spectra of the corresponding esters and amides showed strong consistency with the absolute configuration of the carbinol and amine moieties, whose observed ΔδL1 and ΔδL2 values were in the ranges of 0.1-0.4 and 0.02-0.12 ppm, respectively.