1357271-91-0Relevant academic research and scientific papers
Click chemistry: An efficient synthesis of heterocycles substituted with steroids, saponins, and digitalis analogues
Deobald, Anna M.,Camargo, Leandro R. S.,Alves, Diego,Zukerman-Schpector, Julio,Correa, Arlene G.,Paixao, Marcio W.
, p. 4003 - 4010 (2012/01/05)
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been used for the construction of 1,2,3-triazole containing steroids in good to excellent yields. Combination of propargylic glycosides and steroidal azides as reaction partner allowed the synthesis of a privileged class of natural product analogues. The versatility of this protocol makes this chemistry a useful attractive approach for the synthesis of target molecules. Georg Thieme Verlag Stuttgart · New York.
