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(S,R)-Palonosetron Hydrochloride, also known as P165800, is a potent and selective antagonist of the 5-HT3 receptor. It is an enantiomer of Palonosetron, which is a drug used to treat various conditions related to the 5-HT3 receptor. The compound exhibits its effects through its interaction with the 5-HT3 receptor, which is involved in the transmission of serotonin, a neurotransmitter that plays a crucial role in various physiological processes.

135729-76-9

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135729-76-9 Usage

Uses

Used in Pharmaceutical Industry:
(S,R)-Palonosetron Hydrochloride is used as an active pharmaceutical ingredient for the development of medications targeting the 5-HT3 receptor. Its application is primarily due to its potent and selective antagonistic properties, which can help in the treatment of conditions such as nausea, vomiting, and other serotonin-related disorders.
Used in Research and Development:
(S,R)-Palonosetron Hydrochloride is used as a research compound for in vitro studies involving the 5-HT3 receptor. Its application in this context is to help scientists understand the receptor's role in various physiological processes and to develop new drugs or therapies that can modulate its activity.
Used in Quality Control and Impurity Testing:
(S,R)-Palonosetron Hydrochloride is also used as an impurity in the quality control and testing of Palonosetron and its related pharmaceutical products. Its application in this context is to ensure the purity, safety, and efficacy of the final drug product by identifying and quantifying the presence of this specific impurity.

Check Digit Verification of cas no

The CAS Registry Mumber 135729-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,2 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 135729-76:
(8*1)+(7*3)+(6*5)+(5*7)+(4*2)+(3*9)+(2*7)+(1*6)=149
149 % 10 = 9
So 135729-76-9 is a valid CAS Registry Number.

135729-76-9 Well-known Company Product Price

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  • USP

  • (1492244)  Palonosetron Related Compound C  United States Pharmacopeia (USP) Reference Standard

  • 135729-76-9

  • 1492244-15MG

  • 14,500.98CNY

  • Detail

135729-76-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3aR)-2-(1-Azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-b enzo[de]isoquinolin-1-one hydrochloride (1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:135729-76-9 SDS

135729-76-9Upstream product

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