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Upstream product

• 88768-84-7 1-phenyl-4-trimethylsilylbutane-3-yn-2-one 
• 712329-47-0 1-(azidomethyl)-3,5-dimethoxybenzene 
• 103-80-0 phenylacetyl chloride 
• 1345823-27-9 1-(1-(3,5-dimethoxybenzyl)-1H-1,2,3-triazol-4-yl)-2-phenylethanone 

Relevant academic research and scientific papers

Synthesis and evaluation of α-ketotriazoles and α,β- diketotriazoles as inhibitors of Mycobacterium tuberculosis

Two series of α-ketotriazole and α,β-diketotriazole derivatives were synthesized and evaluated for antitubercular and cytotoxic activities. Among them, two α,β-diketotriazole compounds, 6b and 9b, exhibited good activities (minimum inhibitory concentratio

Synthesis of α,β-diketotriazoles by aerobic copper-catalyzed oxygenation with triazole as an intramolecular assisting group

The catalytic oxidation of α-ketotriazoles to α,β- diketotriazoles was performed with CuCl2 or CuI/2,9-dimethyl-1,10- phenanthroline in air at 80 °C in good yields. Studies showed that the triazole group participates in complexation to the copper and favors oxidation. Copyright