135747-52-3

Basic information

• Product Name: 3-(4-acetylphenyl)-11-(4-chlorophenyl)-7,8,9,10-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one
• Synonyms: 3-(4-acetylphenyl)-11-(4-chlorophenyl)-7,8,9,10-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one
• CAS NO: 135747-52-3
• Molecular Formula: C₂₆H₁₉ClN₄O₂S
• Molecular Weight: 486.97266
• Mol File: 135747-52-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-acetylphenyl)-11-(4-chlorophenyl)-7,8,9,10-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-acetylphenyl)-11-(4-chlorophenyl)-7,8,9,10-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(135747-52-3)
• EPA Substance Registry System: 3-(4-acetylphenyl)-11-(4-chlorophenyl)-7,8,9,10-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(135747-52-3)

Safety Data

• Hazardous Substances Data: 135747-52-3(Hazardous Substances Data)

Upstream product

• 135747-40-9 N-(4-Acetyl-phenyl)-2-[4-(4-chloro-phenyl)-3-cyano-5,6,7,8-tetrahydro-quinolin-2-ylsulfanyl]-acetamide 
• 135747-46-5 3-Amino-4-(4-chloro-phenyl)-5,6,7,8-tetrahydro-thieno[2,3-b]quinoline-2-carboxylic acid (4-acetyl-phenyl)-amide 
• 83236-51-5 2-mercapto-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile 
• 38283-38-4 4-(2-chloroacetamido)acetophenone 

Relevant articles and documents

SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW HETEROCYCLIC QUINOLINE DERIVATIVES

Alkylation of 2-mercapto-3-cyano-4-aryl-5,6,7,8-tetrahydroquinoline (I) gave compounds II-IV.Cyclization of III and IV afforded thienoquinolines V and VI respectively.On diazotization of V and VI, the corresponding triazinone derivatives VII and VIII were obtained.Also, reaction of V with benzoyl chloride yielded the tetracyclic compound IX .Structures of the new compounds were established by their elemental analyses and spectral data.Some of these compounds were screened in vitro for their antibacterial activities.