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2-Amino-2,3-dihydro-thiazolo[4,5-b]pyridin-5(6H)-one, commonly known as rufinamide, is a triazole derivative that functions as an anti-epileptic medication. It exerts its therapeutic effect by modulating the activity of sodium channels in the brain, thereby reducing the frequency and severity of seizures. Rufinamide is particularly effective in treating seizures associated with Lennox-Gastaut syndrome, a severe form of epilepsy that affects both children and adults.

13575-44-5

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13575-44-5 Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-2,3-dihydro-thiazolo[4,5-b]pyridin-5(6H)-one is used as an anti-epileptic medication for the treatment of seizures associated with Lennox-Gastaut syndrome. It is effective in reducing the frequency and severity of seizures in patients with this form of epilepsy, making it a valuable therapeutic option for seizure management.
2-Amino-2,3-dihydro-thiazolo[4,5-b]pyridin-5(6H)-one is used as a sodium channel modulator for its mechanism of action in controlling seizures. It works by stabilizing the inactive state of voltage-gated sodium channels, thereby reducing the abnormal neuronal activity that leads to seizures.
The medication is typically administered orally in tablet or oral suspension form, allowing for convenient and effective treatment. However, its use may be associated with some side effects, including dizziness, headache, and nausea. Despite these potential side effects, rufinamide remains a significant therapeutic option for patients with Lennox-Gastaut syndrome, offering a means to manage their seizures and improve their quality of life.

Check Digit Verification of cas no

The CAS Registry Mumber 13575-44-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,7 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13575-44:
(7*1)+(6*3)+(5*5)+(4*7)+(3*5)+(2*4)+(1*4)=105
105 % 10 = 5
So 13575-44-5 is a valid CAS Registry Number.

13575-44-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-4H-[1,3]thiazolo[4,5-b]pyridin-5-one

1.2 Other means of identification

Product number -
Other names 2-Aminothiazolo[4,5-b]pyridin-5(4H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13575-44-5 SDS

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