1357577-07-1

Upstream product

• 1357575-01-9 (R)-methyl 3-(benzyloxycarbonylamino)-4-(phenylthio)butanoate 
• 1357575-02-0 (R)-methyl 4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butanoate 
• 1097880-26-6 tert-butyl 4-[(E)-{[(S)-2-methylpropane-2-sulfinyl]imino}methyl]piperidine-1-carboxylate 
• 1357577-24-2 tert-butyl 4-((4'-chlorobiphenyl-2-yl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidine-1-carboxylate 
• 1357577-27-5 ethyl 4-(4-((4'-chlorobiphenyl-2-yl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidin-1-yl)benzoate 
• 1357577-23-1 tert-butyl 4-((2-bromophenyl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidine-1-carboxylate 
• 1357577-26-4 (S)-N-((4'-chlorobiphenyl-2-yl)(piperidin-4-yl)methyl)-2-methylpropane-2-sulfinamide trifluoroacetate 
• 1357576-38-5 4-(4-((R)-(4'-chlorobiphenyl-2-yl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidin-1-yl)-N-(4-((R)-4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide 
• 1357576-37-4 4-(4-((R)-(4'-chlorobiphenyl-2-yl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidin-1-yl)benzoic acid 
• 1357576-34-1 ethyl 4-(4-((R)-(4'-chlorobiphenyl-2-yl)((S)-1,1-dimethylethylsulfinamido)methyl)piperidin-1-yl)benzoate 
• 1357575-05-3 (R)-4-(phenylthio)-3-((4-sulfamoyl-2-((trifluoromethyl)sulfonyl)phenyl)amino)butanoic acid 
• 1357575-04-2 (R)-methyl 3-amino-4-(phenylthio)butanoate, trifluoroacetic acid salt 
• 2358-41-0 1-fluoro-2-[(trifluoromethyl)sulfonyl]benzene 
• 1027345-12-5 [4-((R)-3-morpholin-4-yl-1-phenylsulfanyl-methyl-propylamino)-3-trifluoromethanesulfonyl]benzenesulfonamide 

Relevant academic research and scientific papers

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.