1357620-17-7

Basic information

• Product Name: N-(3-acetamido-5-((tert-butyldimethylsilyloxy)methyl)phenyl)-N'-(3-(dimethylamino)propyl) terephthalamide
• Synonyms: N-(3-acetamido-5-((tert-butyldimethylsilyloxy)methyl)phenyl)-N'-(3-(dimethylamino)propyl) terephthalamide
• CAS NO: 1357620-17-7
• Molecular Weight: 526.751
• Mol File: 1357620-17-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-acetamido-5-((tert-butyldimethylsilyloxy)methyl)phenyl)-N'-(3-(dimethylamino)propyl) terephthalamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-acetamido-5-((tert-butyldimethylsilyloxy)methyl)phenyl)-N'-(3-(dimethylamino)propyl) terephthalamide(1357620-17-7)
• EPA Substance Registry System: N-(3-acetamido-5-((tert-butyldimethylsilyloxy)methyl)phenyl)-N'-(3-(dimethylamino)propyl) terephthalamide(1357620-17-7)

Safety Data

• Hazardous Substances Data: 1357620-17-7(Hazardous Substances Data)

Upstream product

• 1041198-49-5 3-acetamido-5-nitrobenzyl acetate 
• 71022-43-0 3,5-dinitrobenzyl alcohol 
• 1018449-14-3 N-(3-((tert-butyldimethylsilyloxy)methyl)-5-nitrophenyl)acetamide 
• 1018448-89-9 3-acetamido-5-nitrobenzyl alcohol 
• 90390-46-8 (3-amino-5-nitrophenyl)methanol 
• 100-20-9 terephthaloyl chloride 
• 67852-95-3 4-benzyloxycarbonyl-benzoyl chloride 
• 18520-63-3 monobenzyl terephthalate 
• 19851-61-7 p-dibenzyl benzenedicarboxylate 
• 1357620-12-2 benzyl 4-(3-(dimethylamino)propylcarbamoyl)benzoate 
• 1018449-03-0 C₁₅H₂₆N₂O₂Si 
• 1155168-52-7 4-(3-(dimethylamino)propylcarbamoyl)benzoic acid 

Downstream Products

• 1357620-18-8 N-(3-acetamido-5-(hydroxymethyl)phenyl)-N'-(3-(dimethylamino)propyl)-terephthalamide 

Relevant articles and documents

Synthesis and biological activity of benzamide DNA minor groove binders

A range of di- and triaryl benzamides were synthesised to investigate the effect of the presence and nature of a polar sidechain, bonding and substitution patterns and functionalisation of benzylic substituents. These compounds were tested for their antiproliferative activity as well as their DNA binding activity. The most active compounds in all assays were unsymmetrical triaryl benzamides with a bulky or alkylating benzylic substituent and a polar amino sidechain.