1358032-19-5

Basic information

• Product Name: N-(3-fluorophenethyl)-2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxamide
• Synonyms: N-(3-fluorophenethyl)-2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxamide
• CAS NO: 1358032-19-5
• Molecular Weight: 367.42
• Mol File: 1358032-19-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-fluorophenethyl)-2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-fluorophenethyl)-2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxamide(1358032-19-5)
• EPA Substance Registry System: N-(3-fluorophenethyl)-2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxamide(1358032-19-5)

Safety Data

• Hazardous Substances Data: 1358032-19-5(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 6768-23-6 diethyl-2-(4-methoxybenzylidene)malonate 
• 404-70-6 2-(3-Fluorophenyl)ethylamine 
• 1309359-55-4 2-(4-methoxyphenyl)-4-vinyl-2,5-dihydrofuran-3-carboxylic acid 

Relevant articles and documents

Synthesis of novel 2, 5-dihydrofuran derivatives and evaluation of their anticancer activity

According to metal-catalyzed [3 + 2] cycloaddition reaction, we synthesized a series of novel 2, 5-dihydrofuran derivatives and evaluated their in vitro anti-cancer activities via MTT method. The bioassay showed that the majority of the resultant compounds exerted anti-tumor effect against four human cancer cell lines to various extents, which supported the rationale of the design. Compounds 9e and 10g showed the highest activity with broad anti-cancer spectrum, which were good candidates for further evaluation.