135810-01-4Relevant academic research and scientific papers
An expedient large-scale preparation of a dibenz[b,e]oxepinone derivative
Lee, Thomas B.K.,Tebben, Andrew J.,Weiberth, Franz J.,Wong, George S.K.
, p. 747 - 751 (1998)
A convenient, large-scale synthesis of a dibenz[b,e]oxepinone derivative is described. The dibenz[-b,e]oxepinone ring system is constructed using an iron chloride catalyzed intramolecular Friedel-Crafts cyclization of an appropriate phenoxymethylbenzoic acid chloride in toluene, reagents and conditions that are economically and environmentally compatible with large- scale preparation.
