135883-34-0 Usage
Derivative of benzene
1-tert-butyl-3-ethynyl-benzene is derived from benzene, which means it retains the benzene ring structure while having additional functional groups attached to it.
tert-Butyl group
A tert-butyl group (C4H9) is attached to the benzene ring, which is a bulky, non-reactive alkyl group that can influence the compound's reactivity and stability.
Ethynyl group
An ethynyl group (C2H), which is an alkynyl group with a triple bond between the two carbon atoms, is also attached to the benzene ring. This group imparts unique chemical properties to the compound.
Building block in synthesis
1-tert-butyl-3-ethynyl-benzene is commonly used as a starting material in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and materials.
Colorless liquid
The compound appears as a colorless liquid, which is a characteristic of many organic compounds with similar structures.
High boiling point
1-tert-butyl-3-ethynyl-benzene has a high boiling point, which indicates strong intermolecular forces and a relatively high thermal stability.
Moderately toxic
The compound is considered to be moderately toxic, which means it can pose potential health hazards if ingested, inhaled, or absorbed through the skin.
Industrial applications
Due to its unique properties, 1-tert-butyl-3-ethynyl-benzene is useful in various industrial processes, such as the production of chemicals, materials, and pharmaceuticals.
Caution in handling
It is important to handle 1-tert-butyl-3-ethynyl-benzene with care, as it may pose potential health risks. Proper safety measures, such as wearing gloves and using appropriate personal protective equipment, should be followed to minimize exposure and prevent accidents.
Check Digit Verification of cas no
The CAS Registry Mumber 135883-34-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,8,8 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135883-34:
(8*1)+(7*3)+(6*5)+(5*8)+(4*8)+(3*3)+(2*3)+(1*4)=150
150 % 10 = 0
So 135883-34-0 is a valid CAS Registry Number.
135883-34-0Relevant academic research and scientific papers
METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B
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Page/Page column 171, (2008/06/13)
The invention provides methods for treating an individual having a retinoid responsive disorder. In one embodiment, a method involves administering to the individual an effective amount of a selective CYP26B inhibitor, the selective CYP26B inhibitor having at least 10-fold selectivity for CYP26B relative to CYP26A. In another embodiment, a method involves administering to the individual an effective amount of a selective CYP26A inhibitor, the selective CYP26A inhibitor having a chemical formula set forth in the specification. The invention further provides screening methods for identifying a selective CYP26A inhibitor or selective CYP26B inhibitor.
COMPOUNDS HAVING SELECTIVE CYTOCHROME P450RAI-1 OR SELECTIVE CYTOCHROME P450RAI-2 INHIBITORY ACTIVITY AND METHODS OF OBTAINING THE SAME
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Page/Page column 133, (2010/02/12)
Compounds of formulas 1 through 17 provided in the specification specifically or selectively inhibit either the cytochrome P450RAI-1 enzyme or the cytochrome P450RAI-2 enzyme.
Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity
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, (2008/06/13)
Retinoid like activity is exhibited by compounds of the formula STR1 where R1 -R4 independently are hydrogen, lower alkyl, cycloalkyl or lower alkenyl, A and B independently are hydrogen, lower alkyl cycloalkyl, lower alkenyl, SR* or
