135908-33-7

Usage

Uses

Used in Pharmaceutical Industry:
4-AMINOBICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID METHYL ESTER is used as a building block for the synthesis of various drugs and biologically active compounds. Its unique structure allows for the creation of diverse molecular structures, making it a versatile intermediate in medicinal chemistry.
Used in Drug Delivery Systems:
Due to its potential interactions with biological systems, 4-AMINOBICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID METHYL ESTER is studied for its use as a drug delivery system. This application aims to enhance the efficacy and targeted delivery of pharmaceuticals, potentially improving treatment outcomes for various conditions.
Used in Organic Synthesis:
4-AMINOBICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID METHYL ESTER also serves as a valuable intermediate in organic synthesis, where it can be used to produce a wide range of chemical compounds for various applications, further expanding its utility in the chemical and pharmaceutical sectors.

Upstream product

• 18720-35-9 bicyclo[2.2.2]octane-1,4-dicarboxylic acid monomethyl ester 
• 862501-91-5 methyl 4-(((benzyloxy)carbonyl)amino)bicyclo[2.2.2]octane-1-carboxylate 

Downstream Products

• 914619-02-6 4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester 
• 1048367-68-5 methyl 4-(4'-tert-butylbiphenyl-2-ylcarboxamido)bicyclo[2.2.2]octane-1-carboxylate 
• 1379000-33-5 C₁₉H₂₆N₂O₃ 
• 1544656-15-6 4-(((6-((cis-4-methylcyclohexyl)oxy)naphthalen-2-yl)methyl)amino)bicyclo[2.2.2]octane-1-carboxylic acid 
• 943845-74-7 methyl 4-((tert-butoxycarbonyl)amino)bicyclo[2.2.2]octane-1-carboxylate 

Relevant academic research and scientific papers

2,3-DIHYDRO-1H-PYRROLIZINE-7-FORMAMIDE DERIVATIVE AND APPLICATION THEREOF

The present application relates to a 2,3-dihydro-1H-pyrrolizine-7-formamide derivative as a nucleoprotein inhibitor and a use in preparation of a drug for treating HBV related diseases. The present application specifically relates to a compound represented by formula (II), and isomers or pharmaceutically acceptable salts thereof.

NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF

The present invention relates to inhibitors of 11-β-hydroxysteroid dehydrogenase type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.

GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS

Compounds represented by formula (I): are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.

Synthesis and structural activity relationship of 11β-HSD1 inhibitors with novel adamantane replacements

A series of structurally novel and metabolically stable bridged bicyclic carbocycle and heterocycle adamantane replacements have been synthesized and biologically evaluated. Several of these compounds exhibit excellent human and mouse 11β-HSD1 potency and