135913-36-9Relevant academic research and scientific papers
The synthesis of potent marcocyclic renin inhibitors
Dhanoa, Daljit S.,Parsons, William H.,Greenlee, William J.,Patchett, Arthur A.
, p. 1725 - 1728 (2007/10/02)
An efficient synthesis of a novel class of potent macrocylic renin inhibitors exemplified by compounds 1 and 2, which involves the marcocyclization of 8 and 9 as the key step, is described. The macrocyclic design of renin inhibitors 1 and 2 disclosed here
