13594-51-9

Usage

Chemical Properties

White powder

InChI:InChI=1/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m1/s1

Upstream product

• 70-26-8 D-ornithine 
• 151-50-8 potassium cyanide 
• 133906-52-2 L-Citrullinhydantoin 
• 556-89-8 nitrourea 
• 3184-13-2 L-ornithine hydrochloride 
• 117920-63-5 N^α-carbamoyl-(S)-citrulline 
• 74-79-3 L-arginine 
• 70-26-8 L-ornithine 
• 57-13-6 urea 

Downstream Products

• 6692-89-3 N^α-(benzyloxycarbonyl)-L-citrulline 
• 125735-06-0 α-(benzyloxycarbonyl)arginino>succinic acid trimethyl ester 
• 125735-11-7 2-Benzyloxycarbonylamino-5-(2-imino-4-methoxycarbonylmethyl-5-oxo-imidazolidin-1-yl)-pentanoic acid methyl ester 
• 125735-10-6 2-Benzyloxycarbonylamino-5-(5-methoxycarbonylmethyl-4-oxo-4,5-dihydro-1H-imidazol-2-ylamino)-pentanoic acid methyl ester 
• 89499-13-8 N^α-(benzyloxycarbonyl)-L-citrulline methyl ester 
• 125735-05-9 N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester 
• 159858-21-6 (S)-2-((S)-2-((((9H-fluoren-9-yl)-methoxy)carbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid 

Relevant academic research and scientific papers

Urea cycle: Chemical simulation of arginine biosynthesis

We have successfully simulated the salient features of the urea cycle. In this effort an appropriately protected ornithine was transformed to citrulline, via use of a novel amide transfer reagent; the citrulline, in turn, was converted into argininosuccinate which necessitated a new activation procedure to enable acceptance of dimethyl aspartate. Fragmentation of argininosuccinate under carefully controlled conditions afforded arginine. The final step in the cycle, namely, the hydrolysis of arginine to urea and ornithine, has already been accomplished. Amino group transfer from aspartate has also been demonstrated in the conversion of hypoxanthine to adenine.