135950-61-7

Basic information

• Product Name: (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one
• Synonyms: (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one
• CAS NO: 135950-61-7
• Molecular Weight: 232.278
• Mol File: 135950-61-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one(135950-61-7)
• EPA Substance Registry System: (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one(135950-61-7)

Safety Data

• Hazardous Substances Data: 135950-61-7(Hazardous Substances Data)

Upstream product

• 88-15-3 2-Acetylthiophene 
• 459-57-4 4-fluorobenzaldehyde 
• 188290-36-0 thiophene 
• 459-32-5 (E)-4-fluorocinnamic acid 

Downstream Products

• 129122-08-3 (S)-4-[[[4-(4-Fluorophenyl)-2-(1-methylethyl)-6-(2-thienyl)-3-pyridinyl]ethynyl]hydroxyphosphinyl]-3-hydroxybutanoic acid, disodium salt 
• 137586-61-9 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-{[4-(4-fluoro-phenyl)-2-isopropyl-6-thiophen-2-yl-pyridin-3-ylethynyl]-methoxy-phosphinoyl}-butyric acid methyl ester 
• 137586-62-0 (S)-4-{[4-(4-Fluoro-phenyl)-2-isopropyl-6-thiophen-2-yl-pyridin-3-ylethynyl]-methoxy-phosphinoyl}-3-hydroxy-butyric acid methyl ester 
• 137586-59-5 4-(4-Fluorophenyl)-2-(1-methylethyl)-6-(thien-2-yl)-3-pyridinecarboxylic acid,ethyl ester 
• 135426-39-0 3-(2,2-Dibromoethenyl)-4-(4-fluorophenyl)-2-(1-methylethyl)-6-(thien-2-yl)pyridine 
• 135426-18-5 4-(4-Fluorophenyl)-2-(1-methylethyl)-6-(thien-2-yl)-3-pyridinemethanol 
• 137586-60-8 4-(4-Fluorophenyl)-2-(1-methylethyl)-6-(thien-2-yl)-3-pyridinecarboxaldehyde 
• 82127-13-7 4-(4-fluorophenyl)-6-(thiophen-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 85957-62-6 2-(4-chlorophenyl)-4-(4-fluorophenyl)-6-(thiophen-2-yl)pyridine 
• 137586-58-4 2-[1-(4-Fluoro-phenyl)-3-oxo-3-thiophen-2-yl-propyl]-4-methyl-3-oxo-pentanoic acid ethyl ester 
• 351494-47-8 5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide 
• 1428648-18-3 3-(2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4-yl)-2H-chromen-2-one 
• 1428648-17-2 4-(benzofuran-2-yl)-2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole 
• 398471-19-7 4-(4-bromophenyl)-2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole 

Relevant articles and documents

Design and synthesis of spiro derivatives containing a thiophene ring and evaluation of their anti-microbial activity

Synthesis of a series of novel spiro pyrrolidines has been accomplished by 1, 3-dipolar cycloaddition reaction of azomethine ylide generated from phenylalanine and isatin with dipolarophiles in good yield. The reaction proceeded with high regio and stereoselectivity. The products have been characterized by elemental analyses and spectroscopic techniques, namely IR, 1H NMR and 13C NMR spectroscopies. Single crystal analysis of compounds 4k 2D-NMR analysis of compound 4k confirmed the structures of spiropyrrolidine derivatives. These compounds were evaluated for their antimicrobial activity. Most of the synthetic compounds exhibited good activity against microorganisms.

Synthesis, characterization and biological applications of some substituted pyrazoline based palladium (II) compounds

Palladium (II) complexes of the type [PdLCl2] (where L?=?substituted pyrazoline ligands) have been synthesized. The metal complexes (5a-5f) have been characterized by various spectroscopic and analytical techniques like 1H-NMR,

Development of fluorinated thienylchalcones as monoamine oxidase-B inhibitors: Design, synthesis, biological evaluation and molecular docking studies

A series of thienylchalcones with fluoro and trifluoromethyl derivatives were synthesized and evaluated for their capability to inhibit human monoamine oxidase A and B. The chemical structures of the compounds have been ascertained by means of their