82127-13-7

Upstream product

• 135950-61-7 (E)‐3‐(4‐fluorophenyl)‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one 
• 109-77-3 malononitrile 

Downstream Products

• 82127-23-9 3-Amino-4-(4-fluoro-phenyl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carbonitrile 
• 82127-19-3 2-Cyanomethylsulfanyl-4-(4-fluoro-phenyl)-6-thiophen-2-yl-nicotinonitrile 

Relevant academic research and scientific papers

One-pot synthesis of 4,6-diaryl-3-cyanopyridine-2(1H)-thiones and their transformation to substituted thieno[2,3-b;4,5-b]dipyridines and pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidines

4,6-Diaryl-3-cyanopyridine-2(1H)-thiones were synthesized in one step by the reaction of elemental sulfur, malononitrile, and 2-aryl-1-aroylethylenes in the presence of excess triethylamine. The products were used in one-pot syntheses of substituted thien

ACETYL-COA CARBOXYLASE MODULATORS

Provided herein are compounds that exhibit activity as acetyl-CoA carboxylase modulators (e.g., inhibitors) and are useful, for example, in methods for the control of fungal pathogens in plants.