1359670-56-6 Usage
General Description
Anagliptin hydrochloride is a chemical compound that belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It is used in the treatment of type 2 diabetes mellitus to help lower blood sugar levels. Anagliptin hydrochloride works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones in the body. These hormones help stimulate the release of insulin and inhibit the release of glucagon, leading to better glycemic control. Anagliptin hydrochloride is typically administered orally and is well-tolerated with few side effects, making it a valuable option for managing diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 1359670-56-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,9,6,7 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1359670-56:
(9*1)+(8*3)+(7*5)+(6*9)+(5*6)+(4*7)+(3*0)+(2*5)+(1*6)=196
196 % 10 = 6
So 1359670-56-6 is a valid CAS Registry Number.
1359670-56-6Relevant articles and documents
Discovery and pharmacological characterization of N-[2-({2-[(2S)-2- cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a] pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor
Kato, Noriyasu,Oka, Mitsuru,Murase, Takayo,Yoshida, Masahiro,Sakairi, Masao,Yamashita, Satoko,Yasuda, Yoshika,Yoshikawa, Aya,Hayashi, Yuuji,Makino, Mitsuhiro,Takeda, Motohiro,Mirensha, Yakufu,Kakigami, Takuji
, p. 7221 - 7227 (2012/01/05)
In the course of our program for discovery of novel DPP-IV inhibitors, a series of pyrazolo[1,5-a]pyrimidines were found to be novel DPP-IV inhibitors. We identified N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2- methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (4a) and described its pharmacological profiles.
