13599-80-9

Upstream product

• 13599-79-6 4-nitro-benzo[1,2,3]thiadiazole 
• 273-77-8 benzo[1,2,3]thiadiazole 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 92644-29-6 7-phenylazo-benzo[1,2,3]thiadiazol-4-ylamine 
• 92721-75-0 7-(4-chloro-phenylazo)-benzo[1,2,3]thiadiazol-4-ylamine 
• 96078-85-2 N-benzo[1,2,3]thiadiazol-4-yl-toluene-4-sulfonamide 
• 96716-45-9 4-acetylamino-N-benzo[1,2,3]thiadiazol-4-yl-benzenesulfonamide 

Relevant academic research and scientific papers

7-AMINOFUROPYRIDINE DERIVATIVES

Compounds of Formula 1, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by TAK1 or for which an appropriate TAK1 inhibitor is effective. This Abstract is not limiting of the invention.

Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds

Good yields of a range of fluoroaromatic and fluoroheteroaromatic compounds may be obtained by reacting an aromatic or a heteroaromatic amine with a nitrosyl polyfluoro salt in an inert solvent to form an intermediate aryl or heteroaryl diazonium polyfluoro salt and decomposing this aryl or heteroaryl diazonium polyfluoro salt in situ. The process described is especially suitable for the preparation in good yield of fluoroaromatic and fluoroheteroaromatic compounds with ortho substituents.