1360054-35-8

Basic information

• Product Name: (E)-4-bromo-2-(5-hydroxypent-3-enyl)phenol
• Synonyms: (E)-4-bromo-2-(5-hydroxypent-3-enyl)phenol
• CAS NO: 1360054-35-8
• Molecular Weight: 257.127
• Mol File: 1360054-35-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-bromo-2-(5-hydroxypent-3-enyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-bromo-2-(5-hydroxypent-3-enyl)phenol(1360054-35-8)
• EPA Substance Registry System: (E)-4-bromo-2-(5-hydroxypent-3-enyl)phenol(1360054-35-8)

Safety Data

• Hazardous Substances Data: 1360054-35-8(Hazardous Substances Data)

Upstream product

• 1360054-34-7 (E)-ethyl 5-(5-bromo-2-hydroxyphenyl)pent-2-enoate 
• 20921-00-0 6-bromo-3,4-dihydro-2H-1-benzopyran-2-one 
• 109210-20-0 6-bromo-3,4-dihydro-2H-1-benzopyran-2-ol 

Downstream Products

• 1360054-22-3 (E)-5-(5-bromo-2-hydroxyphenyl)pent-2-enyl acetate 
• 1360054-11-0 (E)-5-(5-bromo-2-hydroxyphenyl)pent-2-enyl 2,2,2-trichloroacetimidate 

Relevant articles and documents

Palladium(II)-catalyzed enantioselective synthesis of 2-vinyl oxygen heterocycles

2-Vinylchromanes (1), 2-vinyl-1,4-benzodioxanes (2), and 2,3-dihydro-2-vinyl-2H-1,4-benzoxazines (3) can be prepared in high yields (90-98%) and excellent enantiomeric purities (87-98% ee) by [COP-OAc] 2-catalyzed cyclization of phenolic (E)-allylic trichloroacetimidate precursors. Deuterium-labeling and computational experiments are consistent with these cyclization reactions taking place by an anti-oxypalladation/syn- deoxypalladation mechanism. 2-Vinylchromanes can also be prepared in good yields and high enantiomeric purities from analogous (E)-allylic acetate precursors, which constitutes the first report that acetate is a competent leaving group in COP-catalyzed enantioselective SN2′ substitution reactions.