1360057-99-3

Upstream product

• 104-63-2 N-Benzylethanolamine 
• 110843-90-8 4-benzyl-morpholine-2,3-dione 
• 1360057-98-2 4-benzyl-2-(3,4-dichlorophenyl)-2-hydroxy-morpholin-3-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1360058-00-9 4-benzyl-2-(3,4-dichlorophenyl)-morpholin-3-one 
• 1360058-02-1 C₂₀H₂₁Cl₂NO 
• 1360058-04-3 4-benzyl-2-[(3,4-dichloro-phenyl)-morpholin-2-yl]-acetaldehyde 

Relevant academic research and scientific papers

Preparation of chiral key intermediates of morpholine based neurokinin receptor antagonists by asymmetric allylic alkylation

Abstract The preparation of optically active morpholine-2-aryl-2-allyl derivative from morpholine-2-aryl-3-ones is reported. The optically active tetrasubstituted stereocenter is introduced during a palladium promoted asymmetric allylic alkylation. The re

Synthesis of a chiral key intermediate of neurokinin antagonist SSR 240600 by asymmetric allylic alkylation

The preparation of optically active morpholine-2-aryl-2-acetaldehyde from morpholine-2-aryl-3-one is reported. The quaternary carbon is introduced during a palladium-promoted asymmetric allylic alkylation. This is a useful intermediate in the synthesis an