1360117-48-1

Upstream product

• 1094544-66-7 3-methyl-4-isopropoxyaniline 
• 1360116-54-6 (S)-1-(4-chlorobenzyl)-6-(3-mehyl-4-isopropoxyphenylimino)-3-(2-hydroxycarbonyl-2-methoxyethyl)-1,3,5-triazinane-2,4-dion 
• 1360116-51-3 (S)-1-(4-chlorobenzyl)-6-(3-mehyl-4-isopropoxyphenylimino)-3-(2-methoxycarbonyl-2-methoxyethyl)-1,3,5-triazinane-2,4-dion 
• 1360106-11-1 (S)-1-(4-chlorobenzyl)-6-(ethylthio)-3-(2-methoxycarbonyl-2-methoxy-ethyl)-1,3,5-triazine-2,4(1H,3H)-dion 

Relevant academic research and scientific papers

TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY

The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect. A pharmaceutical composition having an analgesic effect or an improving effect of urination disorder comprising a compound of the formula (I): wherein Rh and Rj are taken together to form a bond; Ra and Rb and/or Rd and Re are taken together to form oxo or the like; Rc is hydrogen, substituted or unsubstituted alkyl or the like; Rf is -(CR4aR4b)n-R2; R4a and R4b are hydrogen, substituted or unsubstituted alkyl or the like; R2 is substituted or unsubstituted cycloalkyl or the like; n is an integer of 1 to 4; -Rg is -X-R3; -X- is -O-, -S- or the like; R3 is substituted or unsubstituted cycloalkyl or the like, or its pharmaceutically acceptable salt or a solvate thereof.