136018-98-9

Upstream product

• 68363-44-0 2-oxo-2-(2-(tritylamino)thiazol-4-yl)acetic acid 
• 135996-12-2 tert-butyl 2-aminoxy-2-(3,4-diacetoxyphenylthio)acetate 
• 135996-11-1 tert-butyl 2-(3,4-diacetoxyphenylthio)-2-(phthalimidoyloxy)acetate 
• 135996-08-6 tert-butyl (3,4-dihydroxyphenylthio)acetate 
• 27320-22-5 4-mercaptobenzene-1,2-diol 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 135996-10-0 tert-butyl 2-chloro-2-(3,4-diacetoxyphenylthio)acetate 
• 135996-09-7 tert-butyl (3,4-diacetoxyphenylthio)acetate 

Relevant academic research and scientific papers

Studies on β-lactam antibiotics - Iv: An improved synthesis of 3-(isothiazolylthiomethyl)cephalosporins and its application to new derivatives

An improved synthesis and in vitro activity of cephalosporins with a (4-carboxy-3-hydroxy-5-isothiazolyl)thiomethyl group at the 3-position and its application to the preparation of new derivatives are described. These compounds showed excellent activity