136030-82-5Relevant academic research and scientific papers
Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates.
Pfeffer, Frederick M,Russell, Richard A
, p. 1845 - 1851 (2007/10/03)
A versatile synthesis of amino acid and peptide functionalised [n]polynorbornane scaffolds is described. The frameworks are constructed using the stereoselective and regioselective cycloaddition of suitably functionalised chiral cyclobutene epoxides with similar norbornenes. The strategies employed allow a range of topologies to be accessed and a number of regioselectively addressable linkage points to be accommodated.
