1360364-21-1Relevant articles and documents
HPK1 ANTAGONISTS AND USES THEREOF
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, (2021/03/19)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.
DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A BICYCLO MOIETY
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, (2017/02/28)
The disclosure provides compounds having formula (I), wherein the substituents are as defined herein. The compounds are useful for modulating the dopamine D3 receptor and for treating conditions associated therewith, such as addictions, drug dependency, and psychiatric conditions.
4-quinazoline amine derivatives and their use
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, (2017/01/31)
A 4-quinazoline amine derivative as represented by formula (1), a pharmaceutical composition comprising the derivative, and an application thereof in preparing medicine for curing cancer. The cancer is a drug-resistant cancer, preferably a cancer resisting an EGFR reversible inhibitor, and more preferably, a cancer resisting gefitinib, erlotinib or lapatinib; alternatively, the cancer carries EGFR mutation.
Azaquinazoline Inhibitors Of Atypical Protein Kinase C
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Paragraph 0349, (2015/12/24)
The present application provides a compound of formula (I) and/or a salt thereof, wherein R1, G, and X are as defined herein. A compound of formula (I) and/or its salts have aPKC inhibitory activity, and may be used to treat proliferative disor