1360431-26-0Relevant articles and documents
Desferrithiocin analogue iron chelators: Iron clearing efficiency, tissue distribution, and renal toxicity
Bergeron, Raymond J.,Wiegand, Jan,Bharti, Neelam,McManis, James S.,Singh, Shailendra
experimental part, p. 239 - 258 (2012/03/10)
The current solution to iron-mediated damage in transfusional iron overload disorders is decorporation of excess unmanaged metal, chelation therapy. The clinical development of the tridentate chelator deferitrin (1, Table 1) was halted due to nephrotoxici