1360445-05-1

Upstream product

• 51483-92-2 6-bromo-1-benzopyran-4(4H)-one 
• 100-63-0 phenylhydrazine 
• 1761-61-1 5-bromosalicyclaldehyde 
• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 1360444-98-9 3-(5-bromo-2-methoxyphenyl)-1-phenyl-1H-pyrazole 
• 78725-40-3 C₁₀H₇BrO₂ 
• 78725-70-9 C₁₀H₉BrO₂ 

Downstream Products

• 1360445-21-1 C₂₅H₂₂N₂O₂ 
• 1360445-31-3 C₂₄H₂₀N₂O₂ 
• 1360444-98-9 3-(5-bromo-2-methoxyphenyl)-1-phenyl-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Novel isoxazole and pyrazole analogs based on natural biphenyl-neolignan honokiol were synthesized and evaluated for their inhibitory activities against nitric oxide production in lipopolysaccharide-activated BV-2 microglial cells. The isoxazole skeleton

Synthesis and neurite growth evaluation of new analogues of honokiol, a neolignan with potent neurotrophic activity

A versatile synthetic route is reported towards the preparation of new analogues for potent neurotrophic agent biaryl-type lignan honokiol. A focused 24-membered library of derivatives containing five different groups at 5′-position of honokiol has been prepared in fair to good overall yields. Compared to the natural product, or to analogues with a short alkyl chain in this position, these new derivatives have lost most of the neurotrophic activity.