1360460-82-7

Basic information

• Product Name: Anlotinib
• Synonyms: Anlotinib HCl;Anlotinib 2HCl
• CAS NO: 1360460-82-7
• Molecular Formula: C23H24Cl2FN3O3
• Molecular Weight: 480.3593632
• Mol File: 1360460-82-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Anlotinib(CAS DataBase Reference)
• NIST Chemistry Reference: Anlotinib(1360460-82-7)
• EPA Substance Registry System: Anlotinib(1360460-82-7)

Safety Data

• Hazardous Substances Data: 1360460-82-7(Hazardous Substances Data)

Upstream product

• 1058156-94-7 4-(4-fluoro-2-methyl-1H-indol-5-yl)oxy-6-methoxy-7-(1-acetaminocyclopropan-1-yl)methyloxyquinoline 
• 1210828-42-4 1-(3-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-2-fluoro-6-nitrophenyl)propan-2-one 
• 649736-31-2 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 
• 286371-49-1 7-(benzyloxy)-4-chloro-6-methoxyquinoline 
• 1058156-90-3 1?[[[4?(4?fluoro?2?methyl?1H?indole?5?yl)oxy?6?methoxyquinoline?7?yl]oxy]methyl]cyclopropylamine 

Relevant articles and documents

Anlotinib hydrochloride intermediate and preparation method of anlotinib hydrochloride

The invention provides an anlotinib hydrochloride intermediate and a preparation method of anlotinib hydrochloride. 4-hydroxy-6-methoxyl-7-GO substituted quinolone and 2-fluorine-3-halogenate-6-bitrotoluene are used for generating 4-(2-fluorine-3-methyl-4

Method for synthesizing anlotinib and hydrochloride thereof

The invention relates to a method for synthesizing anlotinib and hydrochloride thereof. Specifically, the method comprises steps (1) to (3) and step (4) or (5) in the description. According to the method disclosed by the invention, a technological flow is

Quinoline derivatives and preparation method for the crystallization of the

The invention relates to a crystal of a quinoline derivative, a preparation method of the crystal, a pharmaceutical composition comprising the crystal and application of the pharmaceutical composition in the field of medicine, in particular to three crystalline solid manners of quinoline derivative dihydrochloride, namely an A-type crystal, a B-type crystal and a C-type crystal, wherein the A-type crystal and the B-type crystal are crystals basically not containing crystal water molecules and other solvents, and the C-type crystal is the crystal containing two crystal water molecules.