1360464-35-2Relevant academic research and scientific papers
Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2)
Yang, Michael G.,Xiao, Zili,Shi, Qing,Cherney, Robert J.,Tebben, Andrew J.,De Lucca, George V.,Santella III, Joseph B.,Mo, Ruowei,Cvijic, Mary Ellen,Zhao, Qihong,Barrish, Joel C.,Carter, Percy H.
, p. 1384 - 1387 (2012)
We report the synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamides (4) as CCR2 inhibitors for the potential treatment of inflammatory diseases. Several of the compounds display nanomolar binding affinity for CCR2. The in vitro structure-activity
