136053-40-2

Basic information

• Product Name: 4-Methoxy-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene
• Synonyms: 4-Methoxy-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene
• CAS NO: 136053-40-2
• Molecular Weight: 276.526
• Mol File: 136053-40-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Methoxy-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene(136053-40-2)
• EPA Substance Registry System: 4-Methoxy-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene(136053-40-2)

Safety Data

• Hazardous Substances Data: 136053-40-2(Hazardous Substances Data)

Upstream product

• 26119-10-8 2-methoxy-but-1-en-3-yne 
• 4526-07-2 1,4-bis(trimethylsilyl)-1,3-butadiyne 
• 75-77-4 chloro-trimethyl-silane 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 768-60-5 4-methoxyphenylacetylen 

Relevant articles and documents

Regiospesific Synthesis of Polysubstituted Phenols via the Palladium-Catalyzed Enyne-Diyne [4 + 2] Cross-Benzannulation Pathway

An efficient method for the synthesis of polysubstituted phenols via the consecutive palladium-catalyzed enyne-diyne [4 + 2] cross-benzannulation reaction and subsequent deprotection step was developed. In all cases, the reactions proceeded in a regiospecific manner affording the corresponding polysubstituted phenols in good overall yields. It was shown that a more useful one-pot methodology could be applied to the synthesis of polysubstituted phenols 4a-e. The synthetically useful p-methoxyphenylacetylene 13 and its monosilylated derivative 12 were smoothly prepared via exhaustive or partial desilylation of bis-silylated aromatic adduct 8c, respectively.