1360546-70-8Relevant articles and documents
Iridium-catalyzed Asymmetric Hydrogenation of Polycyclic Pyrrolo/Indolo[1,2-a]quinoxalines and Phenanthridines
Hu, Shu-Bo,Zhai, Xiao-Yong,Shen, Hong-Qiang,Zhou, Yong-Gui
, p. 1334 - 1339 (2018)
Owing to the dehydrogenative rearomatization of hydrogenation product and poisoning effect of nitrogen atom, asymmetric hydrogenation of polycyclic nitrogen-containing heteroaromatics is still a great challenge. Herein, through in situ protection of hydro
Elemental Sulfur Mediated Synthesis of Pyrrolo[1,2- a ]quinoxalines from 1-(2-Nitroaryl)pyrroles
Ho, Tuan H.,Phan, Nhu T. A.,Ho, Thuyen T. C.,Tran, Duyen L. M.,Nguyen, Tung T.,Phan, Nam T. S.
, p. 4117 - 4123 (2021/08/03)
Methods to afford pyrrolo[1,2- a ]quinoxalines often require the use of prefunctionalized aniline precursors, transition metals, and/or harsh conditions. Herein we describe a simple coupling of 1-(2-nitroaryl)pyrroles and arylacetic acids, in the presence of elemental sulfur, to furnish the fused heterocycles in good yields. The conditions are compatible with many functionalities including ester, nitrile, halogen, and nitro groups. Use of benzyl alcohols and picoline coupling reagents was also attempted.
Unexpected activated carbon-catalyzed pyrrolo[1,2-a]quinoxalines synthesis in water
Sun, Qi,Liu, Liyan,Yang, Yu,Zha, Zhenggen,Wang, Zhiyong
, p. 1379 - 1382 (2019/05/04)
An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramolecular C–N and C–C bond can be easily constructed in water under mild condition. This reaction features a broad substrate scope, a good tolerance to water and air, metal-free, additive-free and redox reagent-free.
