1360596-92-4Relevant academic research and scientific papers
Highly stereoselective and practical synthesis of α-trichloromethyl amines and 2,2-dichloroaziridines from chloroform
Li, Ya,Zheng, Tao,Wang, Wei,Xu, Wei,Ma, Yingchao,Zhang, Sishi,Wang, Han,Sun, Zhihua
, p. 308 - 312 (2012)
A highly stereoselective and practical synthesis of α-trichloromethyl amines by nucleophilic trichloromethylation of N-(tert-butylsulfinyl)imines with chloroform was achieved. The obtained α-trichloromethyl amines can be further transformed into chiral 2,2-dichloroaziridines through an intramolecular nucleophilic substitution methodology. 2,2-Dichloroaziridines can also be produced directly from chloroform and N-(tert-butylsulfinyl)imines through a one-pot procedure. Copyright
