1360628-02-9Relevant articles and documents
A click chemistry approach to pleuromutilin derivatives, part 2: Conjugates with acyclic nucleosides and their ribosomal binding and antibacterial activity
Dreier, Ida,Kumar, Surender,S?ndergaard, Helle,Rasmussen, Maria Louise,Hansen, Lykke Haastrup,List, Nanna Holmgaard,Kongsted, Jacob,Vester, Birte,Nielsen, Poul
, p. 2067 - 2077 (2012)
Pleuromutilin is an antibiotic that binds to bacterial ribosomes and thereby inhibit protein synthesis. A new series of semisynthetic pleuromutilin derivatives were synthesized by a click chemistry strategy. Pleuromutilin was conjugated by different linke