1360630-63-2

Basic information

• Product Name: methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-4-carboxylate
• Synonyms: methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-4-carboxylate
• CAS NO: 1360630-63-2
• Molecular Weight: 447.511
• Mol File: 1360630-63-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-4-carboxylate(1360630-63-2)
• EPA Substance Registry System: methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-4-carboxylate(1360630-63-2)

Safety Data

• Hazardous Substances Data: 1360630-63-2(Hazardous Substances Data)

Upstream product

• 586-78-7 para-nitrophenyl bromide 
• 14047-29-1 4-carboxyphenylboronic acid 
• 5730-76-7 methyl 4’-amino-[1,1’-biphenyl]-4-carboxylate 
• 56875-59-3 6-methoxy-naphthalene-2-sulfonyl chloride 

Relevant articles and documents

Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

Recent drug discovery programs targeting urokinase plasminogen activator (uPA) have resulted in nonpeptidic inhibitors consisting of amidine or guanidine functional groups attached to aromatic or heteroaromatic scaffolds. There is a general problem of poor oral bioavailability of these charged inhibitors. In this paper, we report the synthesis and evaluation of a series of naphthamide and naphthalene sulfonamides as uPA inhibitors containing non-basic groups as substitute for amidine or guanidine groups.