1360820-18-3

Basic information

• Product Name: (S)-3-(3-methoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine
• Synonyms: (S)-3-(3-methoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine
• CAS NO: 1360820-18-3
• Molecular Weight: 241.29
• Mol File: 1360820-18-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-3-(3-methoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(3-methoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine(1360820-18-3)
• EPA Substance Registry System: (S)-3-(3-methoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine(1360820-18-3)

Safety Data

• Hazardous Substances Data: 1360820-18-3(Hazardous Substances Data)

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 95-55-6 2-amino-phenol 
• 1311291-92-5 3-(3-methoxyphenyl)-2H-benzo[b][1,4]oxazine 

Relevant articles and documents

A metal-free hydrogenation of 3-substituted 2H-1,4-benzoxazines

A metal-free hydrogenation of 3-substituted 2H-1,4-benzoxazines has been successfully realized with 2.5 mol% of B(C6F5)3 as a catalyst to furnish a variety of 3,4-dihydro-2H-1,4-benzoxazines in 93-99% yields. Up to 42% ee was also achieved for the asymmetric hydrogenation with the use of a chiral diene and HB(C6F5)2.

Iridium-catalyzed asymmetric hydrogenation of 3-substituted 2H-1,4-benzoxazines

The highly enantioselective hydrogenation of 3-aryl-2H-1,4-benzoxazines was achieved using the (cyclooctadiene)iridium chloride dimer/(S)-SegPhos/iodine {[Ir(COD)Cl]2/(S)-SegPhos/I2} system as catalyst with up to 92% ee. The 3-styryl