136087-85-9 Usage
General Description
Fidarestat is an aldose reductase inhibitor (ARI), a type of drug typically used for the management of diabetic neuropathy, a common complication of diabetes. This chemical works by blocking the action of the aldose reductase enzyme that is involved in the metabolism of glucose. The inhibition of this enzyme can help prevent or slow down nerve damage in individuals with diabetes. Fidarestat is still in clinical development and has not been approved for general use by regulatory authorities. It is under investigation due to its potential in alleviating symptoms and complications of chronic diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 136087-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,0,8 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 136087-85:
(8*1)+(7*3)+(6*6)+(5*0)+(4*8)+(3*7)+(2*8)+(1*5)=139
139 % 10 = 9
So 136087-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H10FN3O4/c13-5-1-2-7-6(3-5)12(4-8(20-7)9(14)17)10(18)15-11(19)16-12/h1-3,8H,4H2,(H2,14,17)(H2,15,16,18,19)/t8-,12-/m0/s1
136087-85-9Relevant articles and documents
USE OF SUBSTITUTED 2 PHENYLBENZIMIDAZOLES AS MEDICAMENTS
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, (2008/06/13)
The present invention relates to the use of a substituted 2-phenylbenzimidazole of formula I wherein R1, R2, R3, R 4, R5 and m have the meanings given in the claims, for the preparation of a medicament for the treatment or prevention of diseases involving glucagon receptors, as well as new compounds of formula I wherein R1 is a group of formula
Process for preparing optically active hydantoins
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, (2008/06/13)
Hydantoin derivatives and salts thereof, intermediates therefor, process for the preparation thereof, and medicines containing the derivatives, wherein said derivatives have the formula STR1 wherein one of V and W is hydrogen and the other is a halogenome
Hydantoin derivatives for treating complications of diabetes
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, (2008/06/13)
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