1360876-32-9Relevant academic research and scientific papers
A modular approach to the synthesis of 1,4,5-substituted-2-aminoimidazoles
Su, Zhaoming,Peng, Lingling,Melander, Christian
supporting information; experimental part, p. 1204 - 1206 (2012/03/27)
Diversified 1,4,5-substituted-2-aminoimidazoles were rapidly assembled via sequential N-H insertion and Grignard addition to α-diazoesters. Lead compounds were identified as antibiotics against Gram-positive bacteria with an MIC value as low as 2 μg/mL.
