1360876-40-9Relevant academic research and scientific papers
Imidazole Derivatives Useful for Controlling Microbial Growth
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Paragraph 0160; 0161; 0162; 0163, (2013/07/19)
Disclosure is provided for 1,4,5-substituted amino imidazole compounds useful to control microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same.
A modular approach to the synthesis of 1,4,5-substituted-2-aminoimidazoles
Su, Zhaoming,Peng, Lingling,Melander, Christian
, p. 1204 - 1206 (2012/03/27)
Diversified 1,4,5-substituted-2-aminoimidazoles were rapidly assembled via sequential N-H insertion and Grignard addition to α-diazoesters. Lead compounds were identified as antibiotics against Gram-positive bacteria with an MIC value as low as 2 μg/mL.
