136093-38-4Relevant academic research and scientific papers
Oxidative nucleophilic substitution of hydrogen in nitroarenes with phenylacetonitrile derivatives
Makosza, Mieczyslaw,Stalinski, Krzysztof
, p. 8797 - 8810 (2007/10/03)
Tertiary carbanions generated from α-substituted phenylacetonitriles in liquid ammonia add to nitrobenzenes in the para position to form the corresponding σ(H)-adducts which are transformed, depending on the starting nitriles and the reaction conditions, to products of oxidative nucleophilic substitution of hydrogen, ONSH or vicarious nucleophilic substitution, VNS.
Synthesis of new fenmetazole analogues with potential mixed α2-adrenergic antagonistic activity and noradrenaline-uptake inhibiting properties
Melloni,Della Torre,Meroni,Pevarello,Varasi,Bonsignori,Cini,Vaghi,Dostert
, p. 207 - 213 (2007/10/02)
In the search for new antidepressants with a rapid onset of action, fenmetazole analogues, bearing a second phenyl ring in a position previously shown not to be detrimental to affinity and selectivity for the α2-adrenoreceptors, were synthesize
