1361033-99-9Relevant academic research and scientific papers
Ligand-free iron-catalyzed benzylic C (sp3)-H amination of methylarenes with: N -fluorobenzenesulfonimide
Bao, Fengyu,Cao, Yuanbo,Liu, Wenbo,Zhu, Junhao
, p. 27892 - 27895 (2019)
Direct conversion of cheap methylarenes to benzylic amines, which are essential structural units of important drugs, is of great significance. However, the known methodologies suffer from the requirement of noble metal catalysts, heavy metal residues or s
Highly regioselective copper-catalyzed benzylic C-H amination by N-fluorobenzenesulfonimide
Ni, Zhikun,Zhang, Qian,Xiong, Tao,Zheng, Yiying,Li, Yan,Zhang, Hongwei,Zhang, Jingping,Liu, Qun
supporting information; experimental part, p. 1244 - 1247 (2012/03/09)
Primary target: A practical and effective copper-catalyzed amination strategy for synthesizing various benzylic amines from benzylic hydrocarbons is described (see scheme; DCE=1,2-dichloroethane). Xylene substrates can undergo diamination reactions using this method. The remarkable preference for primary over secondary benzylic C-H bonds has been observed for the first time. Copyright
